ijcmcr International Journal of Clinical & Medical Case Reports 2834-250X International Journal of Clinical & Medical Case Reports Case report Differential Diagnosis of Kikuchi-Fujimoto Disease: Rare Presentation of Histiocytic Necrotizing Lymphadenitis Hada Nali Hussain Ujama Shah Bibhant Husain Nagama National Academy of Medical Sciences, Bir Hospital, Kathmandu, Nepal 04 04 2026 7 3 04032026 27032026 © 2026 The Author(s). Published by International Journal of Clinical & Medical Case Reports. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International License (CC-BY 4.0).

Kikuchi-Fujimoto Disease (KFD), also known as Histiocytic necrotizing lymphadenitis, is a rare case of cervical lymphadenopathy. Patients usually present with localized lymphadenopathy, fever and fatigue. [2] Because of the poorly understood etiology, it can be mistaken for an infectious disease or even malignancy [2]. Here we discuss a case of KFD that initially presented with left sided cervical lymphadenopathy. Due to its characteristic overlap with other disorders like Tuberculuos lymphadenitis, bacterial lymphadenitis and lymphoma, KFD remains an arduous diagnosis for physicians. Therefore, one should be made aware of symptoms that can lead to misdiagnosis in patients.

Tuberculosis Lymphadenitis Cervical Lymphadenopathy Lymphoma